Nov 4, 2026 · @https://x.com/myrtlebeachnews
Democrat Annie Andrews carried Greenville County — the state’s most populous county and an Upstate Republican stronghold Donald Trump won by about 22 points in 2024 — on her way to winning South Carolina’s U.S. Senate seat Tuesday. This historic victory showcases how Andrews Flips Greenville with her strategic campaign.
Unofficial election-night totals from Greenville County show Andrews with 107,111 votes (49.8%) to Republican Sen. Darline Graham’s 102,314 (47.5%), a margin of 4,797 votes. That is a swing of roughly 24 points from the 2024 presidential result in the county.
Andrews’ campaign announced the statewide win from her election night rally in Charleston. The Associated Press has called the race for Andrews, emphasizing the moment when Andrews Flips Greenville County.
She beat a liberal establishment candidate hand picked by President Donald Trump. The upstate wasn’t buying Graham as a conservative. Andrews ran to the right of Graham in this cycle.
Andrews won Greenville with a plurality, not a majority: third-party and write-in candidates took about 2.7% combined, marking a pivotal point in the campaign where Andrews Flips Greenville.
| Candidate | Party | Votes | Share |
|---|---|---|---|
| Annie Andrews | Democratic | 107,111 | 49.8% |
| Darline Graham | Republican | 102,314 | 47.5% |
| Kasie Whitener | Libertarian | 3,034 | 1.4% |
| Mark Hackett | Constitution | 2,073 | 1.0% |
| Write-ins | — | 754 | 0.4% |
| Total | 215,286 |
Unofficial election-night final, with 152 of 154 Election Day precincts and all 151 absentee/early precincts reporting. County turnout was 62.08%. Figures are not certified. Source: Greenville County Voter Registration and Elections.
Andrews defeated interim Sen. Darline Graham, who was appointed after her brother, Sen. Lindsey Graham, died in July. Graham called Andrews to concede on election night, according to Andrews’ remarks.
The race’s other candidates were Libertarian Kasie Whitener and Constitution Party candidate Mark Hackett.
The line closest to the Greenville story was aimed at voters who crossed party lines:
“And to the Republicans, independents, and Democrats, who took a chance on a pediatrician and mom of three because you believed that South Carolina should come first — thank you.”
On the result:
“South Carolina, my name may have been on the ballot, but this victory doesn’t belong to me – it belongs to all of you. Because tonight, we have sent a clear message: This Senate seat doesn’t belong to one family, one party, or Washington. It belongs to you — and it always will.”
To voters who backed Graham:
“And to the South Carolinians who did not vote for me — I know we may not agree on everything. And I may not have earned your vote. But I want you to know this: I will be your senator, too.”
On independence from Washington:
“Nobody in Washington recruited me to run. Nobody handed me this seat. Nobody wrote me a script. I owe no one in Washington anything. But I owe the people of South Carolina everything.”

Released by the Andrews campaign from her election night rally in Charleston.
“Hello South Carolina!
What an incredible night!
South Carolina – you have shown the nation what’s possible.
You have shown the nation — that in an era of partisan divides, of vitriol and name calling, in a politics dominated by billionaires, special interests, and insiders in Washington – that we will not bow down. We will not back down. And we will chart our own course.
You have shown the nation that we can come together to defend South Carolina.
And today, you have elected a Senator that will ALWAYS put South Carolina First!
Not only that, you have elected the first pediatrician to the United States Senate!
The first woman South Carolina has ever sent to the United States Senate!
From the bottom of my heart—thank you.
I want to start by thanking Darline Graham. I just spoke to her, and she congratulated us on our victory tonight. Darline, thank you for your public service and your love of South Carolina. I wish you and your family well.
To the heartbeat of our campaign– our volunteers –who worked their tails off and never stopped believing — thank you.
To our state party chairwoman, Christale Spain, the first Black woman to lead our state’s party, who invested in this race, who believed in us, and worked tirelessly to build a stronger South Carolina across all 46 counties. — thank you.
To our incredible staff, who poured their hearts and souls into this race— thank you.
To the thousands of people who welcomed us into their homes, their churches, their businesses, and onto their front porches — thank you.
And to the Republicans, independents, and Democrats, who took a chance on a pediatrician and mom of three because you believed that South Carolina should come first — thank you.
South Carolina, my name may have been on the ballot, but this victory doesn’t belong to me – it belongs to all of you.
Because tonight, we have sent a clear message: This Senate seat doesn’t belong to one family, one party, or Washington. It belongs to you — and it always will.
We embarked on this journey over 18 months ago. And while it was long and exhausting, and there were plenty of days when I was running on nothing but protein bars, coffee, and giant Diet Cokes from gas stations, it has been the journey of a lifetime.
We took this campaign to every single one of our 46 counties. From small towns and Main Streets to farms and rural communities. From the Blue Ridge Mountains to the swamps of the Midlands and the beaches of the Lowcountry.
I sat on the back of a pickup truck with an eighth-generation farmer in Barnwell who told me it costs $1,900 just to fill her tractor with diesel, and that the farm her family has worked for eight generations may not survive another two years.
I’ve stood shoulder to shoulder with veterans in Ridgeland, tears in their eyes as they told me about friends they’d lost to suicide, their fight for the benefits they’ve earned, and their fear of another generation being sent off to a reckless war.
I’ve spoken with seniors who worked hard their entire lives, raised their families, and did everything right, only to find themselves struggling to get by on their Social Security checks.
I’ve seen neighbors looking out for one another, regardless of political party. Families coming together to help each other through hard times. And church congregations opening their hearts and doors to anyone who needs a helping hand.
This is the South Carolina I know. This is the South Carolina I’m proud to call home. And this is the South Carolina I will fight for every single day in the United States Senate.
And to the South Carolinians who did not vote for me — I know we may not agree on everything. And I may not have earned your vote. But I want you to know this: I will be your senator, too.
I will listen to you. I will show up for you. And I will fight just as hard for you and your children as I would for my own.
That’s the kind of Senator I’ll be.
An independent voice who will work with anyone, Republican or Democrat, to do what’s right for South Carolina. Who will be a brick wall between Washington, D.C., and South Carolina — even when that means standing up to my own party.
Nobody in Washington recruited me to run. Nobody handed me this seat. Nobody wrote me a script.
I owe no one in Washington anything. But I owe the people of South Carolina everything.
And that’s exactly who I’ll answer to.
I never imagined I’d end up in politics. Since I was 4, I’ve only ever dreamed of becoming a doctor.
And for the past 20 years, I’ve dedicated my life to caring for children in hospitals.
But what I saw as a pediatrician and what I’ve experienced raising my own three kids, made me realize I couldn’t just sit on the sidelines anymore.
I watched insurance companies stand between sick children and the care they desperately needed.
I’ve seen how the decisions made in Washington affect the lives of the children and families I’ve cared for.
That’s why I decided to run, because I believe we have a responsibility to leave our children something better than what we inherited.
A South Carolina where a family can afford to fill up the gas tank, put groceries on the table, and get their child the care they need without worrying about going broke.
Where decisions about our communities are made by the people who live in them, not by billionaires or data center developers.
And where the next generation can afford to build a life and raise a family here.
That’s the future I’m going to fight for.
I know the work ahead won’t be easy. But after 18 months, 46 counties, and everything we’ve been through together, I’ve never been more certain of one thing:
South Carolina’s best days are still ahead of us.
And I promise you, I will give everything I have to make sure we get there.
To build a South Carolina you can afford. A South Carolina you can always call home. And a South Carolina that will always come first.
Thank you for believing in me. Thank you for making history tonight.
And most importantly, thank you to my family.
To my parents, who have stood by me every step of the way.
And to my three children: Thank you for every hug, every word of encouragement. I love you more than words can ever express.
And being your mom will always be the most important job I will ever have.
And I hope that when you look back on this moment, you remember something.
You can stand up for what you believe in. You can speak out when something isn’t right. And no matter how big the challenge, you should never be afraid to try to make things better.”
Andrews Flips Greenville – Greenville County unofficial election-night results
Andrews Flips Greenville – AP via PBS News: Annie Andrews wins Senate race in South Carolina
Andrews Flips Greenville – County swing table, 2024 vs. 2026 (AP/NBC data)
Andrews Flips Greenville – 2026 U.S. Senate election in South Carolina (Wikipedia)
Andrews Flips Greenville – Andrews campaign press release, Nov. 3, 2026